CALL FOR PAPERS Stem Cell Physiology and Pathophysiology PEDF-derived peptide promotes skeletal muscle regeneration through its mitogenic effect on muscle progenitor cells
نویسندگان
چکیده
Tsung-Chuan Ho, Yi-Pin Chiang, Chih-Kuang Chuang, Show-Li Chen, Jui-Wen Hsieh, Yu-Wen Lan, and Yeou-Ping Tsao Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan; Department of Rehabilitation Medicine, Mackay Memorial Hospital, Taipei, Taiwan; Department of Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan; Institute of Biotechnology, National Taipei University of Technology, Taipei, Taiwan; College of Medicine, Fu-Jen Catholic University, Taipei, Taiwan; Department of Microbiology, School of Medicine, National Taiwan University, Taipei, Taiwan; and Department of Medicine, Nursing and Management College, Taipei, Taiwan
منابع مشابه
PEDF-derived peptide promotes skeletal muscle regeneration through its mitogenic effect on muscle progenitor cells.
In response injury, intrinsic repair mechanisms are activated in skeletal muscle to replace the damaged muscle fibers with new muscle fibers. The regeneration process starts with the proliferation of satellite cells to give rise to myoblasts, which subsequently differentiate terminally into myofibers. Here, we investigated the promotion effect of pigment epithelial-derived factor (PEDF) on musc...
متن کاملSimultaneous Effect of Resistance Training and Stem Cell Injection on Blood Glucose Levels, Insulin Resistance, Caspase 3 And 7 As Indicators of Skeletal Muscle Apoptosis in STZ-Induced Male Diabetic Rats
Background: The aim of the present study was to investigate the simultaneous effect of resistance training and stem cell injection on the levels of some indicators of skeletal muscle apoptosis in STZ-induced diabetic male rats. Methods: In this study, 30 rats were randomly divided into 5 groups. Rats in the diabetic group and the diabetic group + stem cell injection had a total of 17 sessions...
متن کاملThe Effect of Resistance Training and Endothelial Stem Cell Injection on Skeletal Muscle Oxidant and Antioxidant Status in STZ-Induced Diabetic Male Rats
Background: Because insulin therapy cannot properly control the progression of diabetes and its complications, other alternative therapies may be desirable. The aim of this study was to investigate the effect of resistance training and endothelial stem cell injection on skeletal muscle oxidant and antioxidant status in STZ-induced diabetic male rats. Method: In this experimental study, 36 male...
متن کاملNeural Stem Cell-based Intraocular Administration of Pigment Epithelium-derived Factor Promotes Retinal Ganglion Cell Survival and Axon Regeneration after Optic Nerve Crush Injury in Rat: An Experimental Study
Background: Pigment epithelium-derived factor (PEDF) is regarded as a multifunctional protein possessing neurotrophic and neuroprotective properties. PEDF has a very short half-life, and it would require multiple injections to maintain a therapeutically relevant level without a delivery system. However, multiple injections are prone to cause local damage or infection. To overcome this, we chose...
متن کاملThe effect of bone marrow mesenchymal stem cells on recovery of skeletal muscle after neurotization surgery in rat
Objective(s): When the nerve is injured near its entrance to the muscle belly, we cannot perform conventional methods. One useful method in such a situation is neurotization surgery. In this study, Bone marrow mesenchymal stem cells (BMSCs) implanted into the paralyzed muscle after neurotization surgery. These cells can stimulate axon growth and motor endplate formation, also prevent muscle atr...
متن کامل